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Cross Ethnics Genome Wide Meta-Analysis

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About Course

Course Overview

Conduct cross-ethnic genome-wide meta-analysis and gene-based rare variant association studies. Master FGWAS methodology, Bayesian approaches, and multi-population analysis techniques.

What You Will Learn

  • Meta-analysis methods (fixed-effect, random-effect, MANTRA)
  • Cross-ethnic GWAS design and challenges
  • Gene-based association tests (SKAT, SKAT-O, burden tests)
  • Rare variant analysis strategies
  • Trans-ethnic fine mapping
  • Functional annotation and variant prioritization

Prerequisites

Strong statistics background. Completion of GWAS fundamentals course recommended.

Duration

6 weeks, 3-4 hours per week

Level

Advanced

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